Grant recieved in 2023

DCCC has founded 150.000 DKK to the initiative.

Locally advanced cervical cancer is treated with a combination of external radiotherapy and concomitant chemotherapy followed by internal radiotherapy. This treatment is associated to several both acute and late side eff ects from neighboring, healthy organs at risk, such as diarrhea, incontinence and aff ection of the immune system.

The group behind the application aims to investigate the potential of minimizing side effects by replacing external X-ray treatment with proton beam therapy. Proton beams allow for more precise delivery, reducing the radiation dose to the surrounding healthy tissue. Consequently, this is anticipated to result in fewer side effects and an enhanced quality of life post-treatment.

DCCC supports the preparation of a nationally investor-initiated study aimed at investigating the efficacy of proton beam therapy. The study aims to evaluate whether this approach could potentially emerge as a novel treatment modality for patients with advanced cervical cancer.

Multidisciplinary organsation
The protocol is anchored in the Danish Gynecological Cancer Group and involves participation from the three centers treating cervical cancer in Denmark: Rigshospitalet, Odense University Hospital, and Aarhus University Hospital, as well as the Danish Centre for Particle Therapy.

Project stakeholder

  • Camilla Kronborg, Consultant, PhD, Danish Centre for Particle Therapy, Aarhus University Hospital. Primary contact, e-mail: camkro@rm.dk
  • Hanne Mathiesen, Consultant, Department of Oncology, Rigshospitalet 
  • Gitte-Bettina Nyvang, Consultant, Department of Oncology, Odense University Hospital
  • Simon Buus, Consultant, Department of Oncology, Aarhus University Hospital