Grant received in 2021
DCCC has funded 152.000 DKK to the project
Women ≥70 years with advanced ovarian cancer are offered less extensive or no surgery due to age, even if it is well-known, that removal of all tumor is the key factor for prognosis and survival. Our aim is to find a combination of screening tools (incl. functional test and biomarkers) to identifying frail patients and to examine the impact of rehabilitation before and during their oncological treatment.
It is a nationwide randomized project, involving specialist teams in oncology, gynecology and geriatrics. Patients eligible for primary chemotherapy will be randomized 1:1 for standard care vs. a comprehensive geriatric assessment and tailored intervention (prehabilitation).
We will develop a frailty screening test, which can select ovarian cancer patients, who needs pre-habilitation prior to treatment and evaluate if intervention results in increased surgical rates. This may decrease the stress of surgery/chemotherapy and complications and improve survival and quality of life.
Multidisciplinary organisation
Dansk OnkoGEriatrisk Netværk (DCCC AGE). Projektet planlægges forankret i Dansk Gynækologisk Cancer Gruppe (DGCG)
Project stakeholders
Central Denmark Region
- Professor, Nurse, Lene Seibæk, Depart. of Gynecology, Aarhus University Hospital
Capital Region of Denmark
- Professor, Consultant, Claus Høgdall Depart. of Gynecology, Rigshospitalet
- Cecilia Lund, Geriatric Depart., Herlev University Hospital
- Unknown oncologist, Rigshospitalet or Herlev University Hospital
- Clinical Research Nurse, Lisssen Ingvardsen, Depart. of Gynecology Rigshospitalet
Region of Southern Denmark
- Professor, Consultant, Jan Blaakjær, Depart. of Gynecology, Odense University Hospital
- Head of Research, Consultant, Jesper Ryg, Geriatrisk Afdeling, Odense University Hospital
- Consultant, PhD, Trine Lembrecht Jørgensen, Depart. of Oncology, Odense University Hospital. Primary contact, e-mail: tine.henrichsen.schnack@rsyd.dk
- Unknown Clinical Research Nurse
Region Zealand
- Professor, Head of Research, Consultant, Jørn Herrstedt, Depart. of Oncology, Region Zealand
- Specialty Registrar, Christina Daviou, Depart. of Gynecology, Roskilde University Hospital
- Unknown Clinical Research Nurse/coordinating nurse
Arrangementer
Dagsmøde om FRAGINOC-studiet