Received grant in 2018

Personalised medicine is rapidly admitted in cancer treatment and now Danish cancer patients with no other treatment options can have a genetic cancer analysis. A national panel of experts can hereafter recommend the patient an experimental treatment directly targeted at specific gene changes. Nevertheless, the access to targeted treatments and knowledge about the most effective medicine is lacking.

We will initiate a clinical test of approved, targeted treatments where patients are offered personalised therapy determined by the result of a genetic cancer analysis.

Multidisciplinary organisation
National collaboration between experimental cancer treatment units in Denmark in the framework of NEXT Center for Oncology and Haematology. National collaboration on bioinformatics and variant calling as well as networks within DCCC and NEXT Center for Bioinformatics.

Project stakeholders
International collaborators

  • Emilie de Voest, NKI, PI of the Dutch Rediscovery Trial (DRUP)

University Hospital Rigshospitalet

  • Consultant, Morten Mau-Sørensen,
  • Professor, Head of Department Ulrik Lassen; Department of Oncology
  • Chief Physician Kristoffer Rohrberg; The Phase I Unit, Department of Oncology
  • Senior Specialist Registrar Iben Spanggaard, The Phase I Unit, Department of Oncology
  • Chief Physician Martin Hutchings, The Phase I Unit, Department of Oncology and Department of Hematology
  • Professor, Head of Department Finn Cilius Nielsen; Department of Genomic Medicine
  • Head of the NGS facility Olga Østrup; Department of Genomic Medicine
  • Chief Physician Eric Santoni-Rugiu; Department of Pathology
  • Chief Physician Jane Preuss Hasselby; Department of Pathology

Aarhus University Hospital

  • Head of Research, Professor Signe Borgquist; Department of Oncology
  • Chief Physician Morten Ladekarl; Department of Oncology
  • Chief Physician Britt Elmedahl Laursen; MOMA
  • Associate Professor Nicolai Birkbak, MOMA
  • Professor Francesco d’Amore; Department of Hematology
  • Professor Torben Steinicke; Department of Pathology

Odense University Hospital

  • Professor Marianne Ewertz; Department of Oncology
  • Chief Physician, Head of Experimental Unit, Karin Holmskov Hansen; Department of Oncology
  • Senior Specialist Registrar Annette Raskov Kodahl; Department of Oncology
  • Professor Bjarne Winther Kristensen; Department of Pathology
  • Professor Thomas Kielsgaard Kristensen; Department of Pathology
  • Professor, Head of Research Henrik Ditzel; Department of Oncology
  • Professor Niels Abildgaard; Department of Hematology

Herlev-Gentofte University Hospital

  • Professor Dorte Nielsen; Department of Oncology
  • Senior Physician Rikke Eefsen; Department of Oncology
  • Professor Estrid Høgdahl; Department of Pathology

Lillebaelt Hospital, Vejle

  • Consultant, Ass. Professor Lars Henrik Jensen; Department of Oncology
  • Registrar Louise Raunkilde Larsen; Department of Oncology
  • Molecular Biologist Rikke Fredslund Andersen; Department of Clinical Biochemistry

Aalborg University Hospital

  • Professor Ursula Falkmer; Department of Oncology
  • Head of Department Paw Jensen; Department of Hematology
  • Associate professor, senior speciality registrar Anne Stidsholt Roug; Department of Hematology
  • Professor Karen Dybkær; Department of Hematology