Tværfaglig/faglig organisation
Nationalt samarbejde mellem de eksperimentelle kræftbehandlingsenheder i Danmark, i regi af NEXT Centre for Onkologi og Hæmatologi. Nationalt samarbejde om bioinformatik og variant calling, netværk i DCCC og i NEXT center for Bioinformatik.

Projektbeskrivelse
Personlig medicin vinder hastigt indpas i kræftbehandling og nu kan danske kræftpatienter med udtømte behandlingsmuligheder få foretaget en kræft-genanalyse. Et nationalt panel af eksperter kan herefter anbefale patienten en eksperimentel behandling rettet mod bestemte genforandringer. Imidlertid mangler der stadig adgang til målrettede behandlinger og viden om, hvilke lægemidler der er mest effektive. Vi påbegynder derfor en klinisk afprøvning af godkendte, målrettede behandlinger, hvor patienterne tilbydes en personlig behandling bestemt af resultatet af en kræft-genanalyse.

Primær kontaktperson
Morten Mau-Sørensen, paul.morten.mau-soerensen@regionh.dk

Projektgruppe

International collaborators

  • Emilie de Voest, NKI, PI of the Dutch Rediscovery Trial (DRUP)

Participants in the research project

University Hospital Rigshospitalet

  • Professor, Head of Department Ulrik Lassen; Department of Oncology
  • Chief Physician Kristoffer Rohrberg; The Phase I Unit, Department of Oncology
  • Senior Specialist Registrar Iben Spanggaard, The Phase I Unit, Department of Oncology
  • Chief Physician Martin Hutchings, The Phase I Unit, Department of Oncology and Department of Hematology
  • Professor, Head of Department Finn Cilius Nielsen; Department of Genomic Medicine
  • Head of the NGS facility Olga Østrup; Department of Genomic Medicine
  • Chief Physician Eric Santoni-Rugiu; Department of Pathology
  • Chief Physician Jane Preuss Hasselby; Department of Pathology

Aarhus University Hospital

  • Head of Research, Professor Signe Borgquist; Department of Oncology
  • Chief Physician Morten Ladekarl; Department of Oncology
  • Chief Physician Britt Elmedahl Laursen; MOMA
  • Associate Professor Nicolai Birkbak, MOMA
  • Professor Francesco d’Amore; Department of Hematology
  • Professor Torben Steinicke; Department of Pathology

Odense University Hospital

  • Professor Marianne Ewertz; Department of Oncology
  • Chief Physician, Head of Experimental Unit, Karin Holmskov Hansen; Department of Oncology
  • Senior Specialist Registrar Annette Raskov Kodahl; Department of Oncology
  • Professor Bjarne Winther Kristensen; Department of Pathology
  • Professor Thomas Kielsgaard Kristensen; Department of Pathology
  • Professor, Head of Research Henrik Ditzel; Department of Oncology
  • Professor Niels Abildgaard; Department of Hematology
    Herlev-Gentofte University Hospital
  • Professor Dorte Nielsen; Department of Oncology
  • Senior Physician Rikke Eefsen; Department of Oncology
  • Professor Estrid Høgdahl; Department of Pathology

Lillebaelt Hospital, Vejle

  • Consultant, Ass. Professor Lars Henrik Jensen; Department of Oncology
  • Registrar Louise Raunkilde Larsen; Department of Oncology
  • Molecular Biologist Rikke Fredslund Andersen; Department of Clinical Biochemistry

Aalborg University Hospital

  • Professor Ursula Falkmer; Department of Oncology
  • Head of Department Paw Jensen; Department of Hematology
  • Associate professor, senior speciality registrar Anne Stidsholt Roug; Department of Hematology
  • Professor Karen Dybkær; Department of Hematology
  • Professor Martin Bøgsted; Department of Hematology