Contact
Anne-Marie Bach
Head of Secretariat
Anne-Marie.Bach@regionh.dk, phone: (+45) 42 94 42 62
Hans Skovgaard Poulsen
Co-Director
Ulrik Lassen
Director
The organisation of the project & governance. The program is organised into a Project Coordination team (Board of Directors) coordinating the overall structure and key decision of the project. A Steering Group is composed of Principal Investigators, work packages leaders, and is responsible for the coordination between the WPs, and ensures the project’s short- and long term progress. The Steering Group is also represented by a patient and The Danish Brain Tumor Association.
Diagnosis molecular profiling:
WP1: Molecular characterization and identification of clonal evolution
WP2: Ex vivo high-throughput Drug screening of GBM patient-derived cells
WP3: Identification and profiling and malignant, migratory cells
WP4: Precision medicine for GBM patients
WP5: Identification and validation of novel therapeutic targets
WP6: Monitoring cell-free DNA in plasma and tracking tumour mutations in tissue and sequential plasma samples in patients with newly diagnosed brain cancer
Treatment:
WP7: Nanocarrier-based drug delivery for next generation glioblastoma therapy
WP8: Magnetic Resonance guided Laser Interstitial Thermal Therapy (MRgLITT) as supplementary treatment for Brain Cancer
WP9: Synaptic input to brain tumors in humans - potential implications for tumor growth, epilepsy and cancer treatment
WP10: Personalised radiotherapy for GBM
WP11: National Quality Assurance program for radiotherapy delineation
WP12: Radiotherapy and advanced imaging
WP13: Antibody-drug conjugate based GBM targeting approach
WP14: Selection of targeted therapies and clinical trial
WP15: ProTarget: A Danish Nationwide Clinical Trial on Targeted Cancer Treatment based on Genomic Profiling
WP16: Theranostics and molecular imaging for glioblastoma
Data collection, interpretation and modelling:
WP17: Non-interventional study and collection of Real-world-data (RWD)
WP18: Shared decision-making in glioblastoma patients – treatment decisions, patient involvement, and emotional well-being
WP19: Physiological MRI for treatment prognosis and responce monitoring of GBM
WP20: Patient-centric data modeling