Grant received in 2022
DCCC has funded 200,000 DKK to the project
During radiotherapy of cancer patients it is important that the radiation will cover the tumor precisely while avoid hitting the healthy
tissue. Therefore, a CT-scan is acquired and both tumor and healthy tissue is delineated. Unfortunately, on a CT-scan it is often hard to distinguish between tumor and healthy tissue.
For this reason, a MR-scan is often acquired, where the difference is more obvious. But using a MR-scan leads to some disadvantages: It takes a long time to acquire, it must be registered to the CT-scan and there is a risk of image-distortion, leading to incorrect delineation. A new technique called Dual-Energy CT (DECT) may give us the best from both the CT- and MR-scan and therefore replace these scans.
The purpose of this project is to start up a national protocol with the goal to clarify the possibilities with DECT on about 20 patients with bony metastasis.
The focus of the study will be on precise delineation of tumor and nerve roots when performed on a DECTscan.
Multidisciplinary organisation
The study is anchored in DCCC Radiotherapy – The Danish National Research Center (DCCC-RT) via ‘IP15’ (Radiotherapy of oligometastatic disease) and ‘WP4’ (Image guided and adaptive radiotherapy).
Project stakeholder
Herlev:
- Gitte Persson, Clinical Research Associate Professor, Chief Physician, PhD, Dept. for Cancer Treatment, Herlev / Gentofte Hospital
- Mette Felter, Departmental Physician, Dept. for Cancer Treatment, Herlev / Gentofte Hospital
- Michael Brun Andersen, Chief Medical Officer, Department of Radiology, Herlev / Gentofte Hospital
- Jens Edmund, Hospital Physicist, PhD, Radiotherapy Research Unit, Dept. for Cancer Treatment, Herlev / Gentofte Hospital
Odense:
- Tine Schytte, Chief Physician, Professor, Department of Oncology, Odense University Hospital
- Tine Bjørn Nielsen, Hospital Physicist, PhD, Radio Physics Laboratory, Odense University Hospital
Aalborg:
- Laurids Østergaard Poulsen, Clinical Research Lecturer, Chief Physician, PhD, Department of Oncology, Aalborg University Hospital
- Martin Skovmos Nielsen, Research Manager Hospital Physicist, PhD, Department of Medical Physics, Aalborg University Hospital
- Hella Sand, Hospital Physicist, Department of Medical Physics, Aalborg University Hospital
- Jimmi Søndergaard, Chief physician, PhD, Head of department, Aalborg University Hospital. Primary contact, e-mail: jiso@rn.dk