Grant received in 2022
DCCC has funded 200,000 DKK to the project
Recently, genomic research of glioblastoma has led to new discoveries of the composition of tumor. This has led to new theories on treating the cancer with immunotherapy, which, have improved survival in many other cancers. Glioblastoma however, which is an incurable type of brain cancer, has not yet been able to take part in this development.
The possible reasons for the missing development are many, including not taken the personal mutational landcape into account. So far, the knowledge on proteomics from the patients' mutations are limited. We need to increase knowledge on personal translational medicine in battling glioblastoma.
We want to initiate a national project of proteomics based upon the patients’ tumor genome sequencing. We want to investigate changes over time.
This trial will be a national translational collaboration between the Novo Nordisk Foundation Center for Protein Research at the University of Copenhagen, Genomic Departments and neuro-oncological departments.
Multidisciplinary organisation
DCCC-Brain Tumor Center, Novo Nordisk Foundation Center for Protein Research, Copenhagen University, DNOG – Dansk Neuroonkologisk gruppe (Danish Neurooncological Group) (DMCG for braintumour)
Project stakeholder
Rigshospitalet
- Associate Professor, MD, Hans Skovgaard Poulsen, DCCC-Brain Tumor Center
- Clinical professor, chief physician, Ulrik Lassen, Department of Clinical Oncology and DCCC-Brain Tumor Center. Primary contact, e-mail: ulrik.lassen@regionh.dk
- Clinical Assistant, Physician, Simone Bendix Maarup, DCCC-Brain Tumor Center
- Departmental Physician, PhD, Benedikte Hasselbalch, DCCC-Brain Tumor Center
Odense University Hospital
- Departmental Physician, PhD, Rikke Dahlrot, Department of Oncology, Aalborg University Hospital
- Chief Physician, Charlotte Aaquist Haslund, Department of Oncology
Copenhagen University - Senior Researcher, Filip Mundt, PhD, Senior Scientist - Mann lab, Novo Nordisk Foundation Center for Protein Research
The project is backed by DMCG Brain Tumor by;
- René J. Laursen, Chief Physician, PhD, Chairman of the Danish Neurooncological Group (DMCG brain tumor), Department of Neurosurgery, Aalborg University Hospital