Grant received in 2021

DCCC has funded 152.000 DKK to the project

Women ≥70 years with advanced ovarian cancer are offered less extensive or no surgery due to age, even if it is well-known, that removal of all tumor is the key factor for prognosis and survival. Our aim is to find a combination of screening tools (incl. functional test and biomarkers) to identifying frail patients and to examine the impact of rehabilitation before and during their oncological treatment.

It is a nationwide randomized project, involving specialist teams in oncology, gynecology and geriatrics. Patients eligible for primary chemotherapy will be randomized 1:1 for standard care vs. a comprehensive geriatric assessment and tailored intervention (prehabilitation).

We will develop a frailty screening test, which can select ovarian cancer patients, who needs pre-habilitation prior to treatment and evaluate if intervention results in increased surgical rates. This may decrease the stress of surgery/chemotherapy and complications and improve survival and quality of life.

Multidisciplinary organisation
Dansk OnkoGEriatrisk Netværk (DCCC AGE). Projektet planlægges forankret i Dansk Gynækologisk Cancer Gruppe (DGCG)

Project stakeholders
Central Denmark Region

• Professor, Nurse, Lene Seibæk, Depart. of Gynecology, Aarhus University Hospital

 Capital Region of Denmark 

• Professor, Consultant, Claus Høgdall Depart. of Gynecology, Rigshospitalet
• Cecilia Lund, Geriatric Depart., Herlev University Hospital
• Unknown oncologist, Rigshospitalet or Herlev University Hospital
• Clinical Research Nurse, Lisssen Ingvardsen, Depart. of Gynecology Rigshospitalet

Region of Southern Denmark

• Professor, Consultant, Jan Blaakjær, Depart. of Gynecology, Odense University Hospital
• Head of Research, Consultant, Jesper Ryg, Geriatrisk Afdeling, Odense University Hospital
• Consultant, PhD, Trine Lembrecht Jørgensen, Depart. of Oncology, Odense University Hospital. Primary contact, e-mail: tine.henrichsen.schnack@rsyd.dk
• Unknown Clinical Research Nurse

Region Zealand

• Professor, Head of Research, Consultant, Jørn Herrstedt, Depart. of Oncology, Region Zealand
• Specialty Registrar, Christina Daviou, Depart. of Gynecology, Roskilde University Hospital
• Unknown Clinical Research Nurse/coordinating nurse

Arrangementer
Dagsmøde om FRAGINOC-studiet